The
SIChrom™
Accelerated Liquid Chromatograph System
Onyx™
Advantages &
Benefits:
Monolithic
vs. Particle-Based Structure
Until recently, HPLC columns have been made of
particle-based materials, usually silica. By their very nature, small particles,
when packed tightly into an HPLC column, create a significant resistance to the
flow of the solvent/sample mixture along with other limitations highlighted
below.
Traditional Silica "Particle-Based" Column
- Individual
silica particles
- High flow
resistance:
Limits ability to shorten run times
- High
backpressure:
Reduces life of pumps, seals, and column
- Reduced
throughput:
Long run times
- Bed splitting
and voiding possible:
Shortens column life and affects
reproducibility, lowers efficiency
Onyx™
“Monolithic” Column
- Monolithic
porous silica rod
- High flow
rates:
Due to high porosity
- Low
backpressures:
Less stress on system and column
- Increased
throughput:
Significantly shorter run times
- No inlet bed
settling:
Increased reliability, reproducibility, and lifetime, maintains
efficiency
Note:
FIAlab Instruments is not affiliated with
Phenomenex.
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