FIAlab Instruments
  Leaders in Flow Injection Technology

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Lab-On-Valve
Principles


 Lab-On-Valve
Applications
Principles of Sequential
and Bead Injection

Lab-On-Valve
and Bead Injection
Lab-On-Valve
and Sequential Injection

FIAlab-On-Valve - FIAlab's Micro SI, or Lab-on-valve manifold has been designed to micro miniaturize flow injection, sequential injection and bead injection - all within  a single monolithic mezzo fabricated component.  The precisely fabricated instrument integrates a flow  through injection port, working channels and flow through cell in a strategically designed structure, that allows sample dilution, reagent addition, mixing, incubation and reaction rate measurements to be carried out under computer control in the forward/reversed flow/ stopped flow regime. Designed to accommodate spectrophotometric and/or fluorescence detection, the lab-on-valve system is compatible with the MicroSIA,  FIAlab 3000 and FIAlab 3500 instruments furnished with a fiber optic spectrophotometer.

References

1/ "Automated Affinity Capture-Release of Biotin-Containing Conjugates Using a Lab-on-Valve Apparatus Coupled to UV/Visible and Electrospray Ionization Mass Spectrometry", Y Ogata, L Scampavia, J. Ruzicka, C. Scott, M  Gelb, and  F. Turecek, Anal. Chem. 2002, 74, 4702-4708 (click to view, ~143 Kb, pdf format).

2/ "Lab-on-valve: Universal Microflow Analyzer Based on Sequential and Bead Injection", J. Ruzicka, The Analyst, 2000, 6, 1053-1060  (click to view, ~860 Kb, pdf format).

3/ "Micro sequential injection: Fermentation monitoring of ammonia, glycerol, glucose, and free iron using the novel lab-on-valve system", Chao-Hsiang Wu, L. Scampavia, J. Ruzicka, B. Zamost, The Analyst, February Issue 2001 (click to view, ~ 835 Kb, pdf format).

4/ "Microsequential injection: anion separations using ‘Lab-on-Valve’ coupled with capillary electrophoresis", Chao-Hsiang Wu, Louis Scampavia and Jaromir Ruzicka, The Analyst, First published as an Advance Article on the web 10th June 2002 (click to view, ~805 Kb, pdf format).

5/ "Micro-Sequential Injection: A multipurpose Lab-on-Valve for the Advancement of Bioanalytical Assays", Louis D. Scampavia and Jaromir Ruzicka, Department of Chemistry, The University of Washington, Seattle, WA 98195-1700, USA (click to view, ~167 Kb pdf format).

6/ "Micro sequential injection: environmental monitoring of nitrogen and phosphate in water using a “Lab-on-Valve system furnished with a microcolumn", Chao-Hsiang Wu and Jaromir Ruzicka, The Analyst 22nd October 2001

 
Please email or phone FIAlab Instruments for additional product information.
 Email: fialab@flowinjection.com, Voice: 425-376-0450 or 1-800-963-1101,  Fax: 425-376-0451
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