SI in Lab-On-Valve® (LOV) format is a groundbreaking technology that has won an enthusiastic acceptance in the research community for its versatility, and in the routine laboratory for its reliability. Designed to accommodate spectrophotometric, fluorescence, and/or electrochemistry measurements, the SI LOV is used as a platform for a variety of microSI techniques. 

Downscaling of the conventional SI system is achieved by integrating the sampling conduit and flow cell into a micromachined compact structure mounted atop a  conventional multiposition valve.  The SI LOV system operates in the microliter domain.  Sample path volume is minimized by short channel lengths, while channel diameters are kept at 0.8mm ID to prevent clogging from “real life” samples.   The conventional sampling line has been eliminated and instead samples are brought into a flow through  port  by an auxiliary pump, while the system is processing the previous sample.  Because of this the sampling frequency of the SI system in the LOV format is higher than that of conventional SI systems, and the waste production/reagent consumption is significantly less.

The SI LOV’s built in flowcell can be configured for absorbance assays and fluorescence assays, as well as electrochemistry.  Further enhancements can be gained by connecting the LOV to an external detector such as FIAlab’s PMT-FL.

For limited sample and/or reagent volume applications consider the MicroSip miniature autosampler.