Research Articles on FIA and SIA Techniques

"Principles of micro Sequential Injection Analysis in the Lab-on-Valve format and its Introduction into a Teaching Laboratory", Michael S. Decuir, Hannah M. Boden, Andrea D. Carroll* and Jaromir Ruzicka
Department of Chemistry, University of Washington, Box 351700, Seattle, WA, 98195, J. Flow Injection Anal., Vol. 24, No. 2 (2007) 103–108

"Micro Sequential Injection Lab-On-Valve for Process Monitoring and Bioanalytical Assays". Chao-Hsiang “Richard” Wu, Ph.D. and Jennifer L. Liu, Ph.D., Amgen, Inc., Process Analytical Technology, April 2006.

"Automated capture and on-column detection of biotinylated DNA on a disposable solid support Michael Decuir, Ilkka Lahdesmaki, Andrea D. Carr and Jaromir Ruzicka*, Analyst 2007, July 2nd

"A novel approach to real-time monitoring of protein immobilization resulted in the surprising finding that current immobilization protocols are far from optimized", Jaromir Ruzicka,* Andrea D. Carroll and Ilkka Lahdesmaki, Analyst 2006 131 799

"Bead injection for biomolecular assays: Affinity chromatography enhanced by bead injection spectroscopy ", Yan Gutzman, Andrea D. Carroll and Jaromir Ruzicka, Analyst 2006 131 809

"Automated Affinity Capture-Release of Biotin-Containing Conjugates Using a Lab-on-Valve Apparatus Coupled to UV/Visible and Electrospray Ionization Mass Spectrometry", Y Ogata, L Scampavia, J. Ruzicka, C. Scott, M Gelb, and F. Turecek, Anal. Chem. 2002, 74, 4702-4708 (click to view, ~143 Kb, pdf format).

"Lab-on-valve: Universal Microflow Analyzer Based on Sequential and Bead Injection", J. Ruzicka, The Analyst, 2000, 6, 1053-1060 (click to view, ~860 Kb, pdf format).

"Micro sequential injection: Fermentation monitoring of ammonia, glycerol, glucose, and free iron using the novel lab-on-valve system", Chao-Hsiang Wu, L. Scampavia, J. Ruzicka, B. Zamost, The Analyst, February Issue 2001 (click to view, ~ 835 Kb, pdf format).

"Microsequential injection: anion separations using ‘Lab-on-Valve’ coupled with capillary electrophoresis", Chao-Hsiang Wu, Louis Scampavia and Jaromir Ruzicka, The Analyst, First published as an Advance Article on the web 10th June 2002 (click to view, ~805 Kb, pdf format).

"Application of Flow Injection Technique in Pharmaceutical Analysis. Part I.: Spectrophotometric and Chemiluminescence Detection", Petr Solich*, Hana Sklenárová, Miroslav Polášek, Rolf Karlicek (click to view, ~ 102 Kb, pdf format).

"Micro-Sequential Injection: A multipurpose Lab-on-Valve for the Advancement of Bioanalytical Assays", Louis D. Scampavia and Jaromir Ruzicka, Department of Chemistry, The University of Washington, Seattle, WA 98195-1700, USA (click to view, ~167 Kb pdf format).

"Micro sequential injection: environmental monitoring of nitrogen and phosphate in water using a “Lab-on-Valve system furnished with a microcolumn", Chao-Hsiang Wu and Jaromir Ruzicka, The Analyst 22nd October 2001

"J. Wang and E. H. Hansen, Interfacing sequential injection on-line preconcentration using a renewable micro-column incorporated in a ‘lab-on-valve’ system with direct injection nebulization inductively coupled plasma mass spectrometry "J. Anal. At. Spectrom., 2001, 16.,

"Sheath Fluid Control to Permit Stable Flow in Rapid Mix Flow Cytometry", Larry C. Seamer, Frederick Kuckuck, and Larry A. Sklar*, 1999 Wiley-Liss, Inc.

"Sequential injection chromatographic determination of paracetamol, caffeine, and acetylsalicylic acid in pharmaceutical tablets", Dalibor Satnsky, Isabel Neto, Petr Solich, Hana Sklenarov1, M. Conceicao, B. S. M. Montenegro, Alberto N. Araffljo

"Accelerated micro-sequential injection in lab-on-valve format, applied to enzymatic assays", Yan Chen and Jaromir Ruzicka, Department of Chemistry, University of Washington, Box 351700, Seattle, WA 98195, USA, First published as an Advance Article on the web 11th June 2004, The Analyst

"Real-time monitoring of lactate extrusion and glucose consumption of cultured cells using a lab-on-valve system",Craig M. Schulz, Louis Scampavia and Jaromir Ruzicka, University of Washington, Department of Chemistry, PO Box 351700, Seattle, WA 98195, First published as an Advance Article on the web 7th November 2002, The Analyst

"J. Wang and E. H. Hansen, On-line ion exchange preconcentration in a sequential injection lab-on-valve microsystem incorporating a renewable column with ETAAS for the trace-level determination of bismuth in urine and river sediment. Atom. Spectrosc., 22(3) (2001) 312-318.

”Environmental monitoring of water quality by assaying traces of phosphate, nitrate nitrite and ammonia using lab-on-valve system” Chao-Hsiang Wu and J. Ruzicka , The Analyst ( submitted).

“Bioligand interaction assay by flow injection absorptiometry using a renewable biosensor system enhanced by spectral resolution “ J. Ruzicka, The Analyst, 1998, 123, 1617-1623.

“Automated nucleic acid isolation and purification from soil extracts using renewable affinity microcolumns in a sequential injection system” D.P. Chandler, B.L.Schuck, F.J. Brockman and C.J.Bruckner-Lea, Talanta , 1999, 49, 969-983

“Coupling on-line preconcentration by ion-exchange with ETAAS. A novel flow injection approach based on the use of renewable microcolumn as demonstrated for determination of nickel in environmental and biological samples” Jinhua Wang and E. H. Hansen, Anal. Chim. Acta 2000, 424, 223-232.

“From Flow Injection to Bead Injection” J. Ruzicka and L. Scampavia, Anal. Chem. 1999, April 1st, 257A-263A. Tutorial: “Flow Injection” J. Ruzicka , E-monograph on CD-ROM, self published at jarda@flowinjection.com and available free of charge (see bottom of page for additional information)